Deep gray matter and fatigue in MS:
Deep gray matter and fatigue in MS: a T1 relaxation time study.
Division of Clinical Neurology,
B Floor, Medical School,
University Hospital NHS Trust,
Queen’s Medical Centre,
Nottingham, UK.
Fatigue in multiple sclerosis (MS) occurs commonly, sometimes as the earliest symptom. Some MS patients consider fatigue to be their most troublesome complaint, and it has been shown to be an independent predictor of impaired quality of life. Several reports have demonstrated that subcortical gray matter pathology is related to fatigue. We hypothesized that MRI detectable changes in the deep gray matter of MS patients may correlate with fatigue severity.
