Posted on January 31st, 2007

Carbon Monoxide Protects Mice From Multiple Sclerosis

Science Daily — Multiple sclerosis (MS) is a chronic inflammatory 

disorder that causes degeneration of the nerves in the brain and 
spinal cord, leading to various symptoms including muscle weakness 
and pain. Most individuals with MS go through cycles of disease and 
remission, leading to the suggestion that there are regulatory 
mechanisms that counter the disease-causing inflammation.

Using a mouse… read more »

Posted on January 31st, 2007

Improvements in muscle-tendon properties are beneficial to 
balance in multiple sclerosis.

Onambele GL, Degens H.

Institute for Biophysical and Clinical Research into Human Movement,

Manchester Metropolitan University,

Hassall Road, Alsager, 

Stoke-on-Trent, ST7 2HL, UK.

A 63-year-old male was diagnosed with multiple sclerosis (MS) two 
years prior to this investigation. We hypothesized that compromised 
postural balance in MS can be improved by training-induced 
alterations in muscle-tendon properties. Sixteen weeks of strength 
and balance training induced an increase in quadriceps and 
gastrocnemius muscle size, strength… read more »

Posted on January 30th, 2007

Disease evolution in multiple sclerosis.

Ebers GC.

University Dept. of Clinical Neurology, Radcliffe Infirmary, 
Woodstock Road, Oxford OX2 6HE, United Kingdom, 
george.ebers@clneuro.ox.ac.uk.

Multiple sclerosis is a long-term disease that evolves over a 
period of 30 to 40 years with progressive accumulation of unremitting 
disability. When developing treatments for multiple sclerosis, it is 
important to be able to measure accurately the impact of treatments 
on disability progression. An analysis of 31 previous clinical trials 
revealed that small changes in EDSS… read more »

Posted on January 29th, 2007

Long-term experience with current disease-modifying drugs in MS  

Posted on January 28th, 2007

Posted on January 28th, 2007

Rationale and experience with combination therapies in MS

Boggild M. Walton Centre for Neurology and Neurosurgery,

Lower Lane,  Fazakerley, Liverpool,

L9 7LJ, UK.

Standard immunomodulatory therapies for multiple sclerosis reduce  relapses by around thirty percent… read more »

Posted on January 27th, 2007

Posted on January 27th, 2007

More severe disability of North Africans vs Europeans with MS in France.

 Department of Neurology,

Central Hospital,

Nancy, France.

OBJECTIVE:

Posted on January 26th, 2007

Is this typical RRMS or a more progressed form?

Q
I was diagnosed in June 2002. In January 2001, I had numbness in my arm. My doctor thought it was a pinched nerve and when it got better in couple of months, he seemed to be right. In January 2002 the numbness returned but this time in both arms, mainly in the hands but with motor control

Posted on January 23rd, 2007

Treatment for SPMS?

Q
I am paralyzed in my legs and my left arm. Is there any treatment for secondary progressive MS?

A

The interferons, Rebif and Betaseron, have been shown to have an effect on attacks in secondary progressive MS. There is conflicting data on their effects on gradual progression, but many neurologists feel that there is at best a modest effect on gradual progression, and