Phase III Trial Of Oral Cladribine, A Novel Investigational Therapy For Multiple Sclerosis, Begins In The United States May 2006
Serono (drt-x: SEO and NYSE: SRA) announced today that recruitment in the U.S. is beginning for the Phase III CLARITY study (CLAdRIbine Tablets in Treating MS OrallY Study) of oral cladribine for the treatment of patients with relapsing forms of multiple sclerosis (MS). This multi-national study… read more »
Age Of First Menstrual Cycle May Be Related To Age Of MS Onset
Recent study outcomes suggest that among women with multiple sclerosis, the age of the first menstrual cycle may be associated with the age a woman experiences the first symptoms of MS.
To evaluate the affect of hormone changes during a first menstrual cycle on MS risk, the investigators sent a survey to 438 female patients with relapsing-remitting… read more »
What is MS?
Multiple Sclerosis is an inflammatory disease of the central nervous system (CNS) that damages the insulating material that surrounds the nerve fibers in the brain, spinal cord, and nerves of the eyes. The insulating material is called myelin or the myelin sheath and when the sheath is damaged, scars called scleroses result… read more »
Researchers Evaluate Clinical Course Of Progressive MS In Brazilian Patients
New research indicates that the clinical course of progressive multiple sclerosis among Brazilian patients is comparable to the clinical course of MS in other geographical areas.
Previous studies have suggested that MS is more likely to occur in cold-weather areas such as northern Europe and the northern United States. To assess the clinical course and outcomes of progressive MS in… read more »
Women With MS, Sexual Dysfunction May Benefit From Disease-specific Sex Education
Women with multiple sclerosis who also have sexual dysfunction may benefit from disease-specific sex education or counseling, a study published in the June issue of the Journal of Clinical Nursing suggests.
In the study, researchers sought to determine whether education or education plus counseling would better improve symptoms of sexual dysfunction among women with MS.
Sixty-two women with MS were… read more »
Upper Body Function Related To Disability, Mental Function Among Patients With MS
The function of upper body extremities appears to be related to cognitive function and disability level among patients with multiple sclerosis, a new study indicates.
The study authors sought to evaluate the relationship between hand and arm function with cognitive function, disability and fatigue among MS patients. A total of 31 patients with MS were compared with 30… read more »
BRAIN MR Imaging of Relapsing MS Patients Using Ultra-Small-Particle Iron Oxide and Compared with Gadolinium
Chromos signs deal with AppTec for multiple sclerosis drug candidate
Chromos Molecular Systems, Inc., (CHR) has signed a contract with AppTec Laboratory Services, Inc., (AppTec) for scale-up and manufacture of its monoclonal antibody drug product candidate CHR-1103.
Chromos has used its proprietary ACE System to engineer cell lines for CHR-1103; AppTec will scale up and manufacture CHR-1103 for use in preclinical toxicology studies and phase I clinical… read more »
Raise Tysabri’s Price
DUBLIN, May 25, 2006 -(Dow Jones)- Elan Corp. PLC’s (ELN)
Chief Executive Kelly Martin said Thursday there is future “headroom” to raise the price of multiple sclerosis drug Tysabri after its anticipated return to the market in the U.S.
The U.S. Food & Drug Administration will make a final decision on Tysabri’s re-entry by June… read more »
Disease Severity, Sociodemographic Factors May Influence Mental Function, Motor Function Among Patients With MS
Among individuals with MS, the extent of mental and physical functioning appears to be affected by the sociodemographic factors, such as education level, and the severity of MS, a study published in the June issue of the journal Multiple Sclerosis suggests.
Researchers collected data from 166 patients with MS to assess cognitive and motor function as… read more »
