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study on oligoclonal bands in RRMS

Absence of cerebrospinal fluid oligoclonal bands is associated with delayed disability progression in relapsing-remitting MS patients treated with interferon-beta.
Department of Neurological Sciences and Behaviour, University of Siena, Italy.

To assess the role of cerebrospinal fluid oligoclonal bands in determining the clinical outcome in patients with relapsing-remitting multiple sclerosis (RRMS) treated with interferon-beta, we carried out a retrospective, multi-centre, observational study Recruiting 209 RRMS patients from six MS centres from northern, central, and southern areas of Italy under treatment with interferon-beta-1a i.m., interferon-beta-1a s.c.  and interferon-beta-1b s.c. 

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